The world is a complex system, and understanding it scientifically requires advanced computational resources and approaches. Engineers design the most powerful computers on Earth in order to model and simulate physical systems such as global climate, the expansion of the universe, and the behavior of matter at an atomic level. But today, high performance scientific computing means more than just supercomputers running numerical models, expanding to large-scale data analysis, AI and machine learning, visualization, and distributed and heterogeneous hardware systems.

UChicago CS researchers are changing the face of high performance computing (HPC), creating new computing paradigms at scale for understanding physical, biological, social, and ecological systems and answering the most significant questions facing society. Faculty lead efforts to apply the latest AI and data science approaches for scientific discovery, from computational imaging and spectroscopy to bioinformatics, neuroscience, and agriculture. In these areas, as well as in the development and application of new exascale systems such as Aurora, UChicago CS benefits from a strong partnership with Argonne National Laboratory.

Labs & Groups

Globus Labs

Ian Foster, Kyle Chard
Realizing a world in which all research data are reliably, rapidly, and securely accessible, discoverable, and usable.

Large-Scale Systems Group (LSSG)

Andrew A. Chien
Exploring critical systems research questions underlying sustainable, scalable large-scale systems, including cloud, high performance, edge, and mobile/IoT computing.

Chameleon

Kate Keahey, Haryadi Gunawi
A configurable experimental environment for large-scale edge to cloud research.

Center for Translational Data Science

Robert Grossman
A research center developing the discipline of translational data science and applying to advance biology, medicine, healthcare and environmental research.

Related Faculty

Kyle Chard

Kyle Chard

Research Associate Professor of Computer Science
Andrew A. Chien

Andrew A. Chien

William Eckhardt Distinguished Service Professor of Computer Science

Anshu Dubey

Senior Scientist, CASE Affiliate
Todd Dupont

Todd Dupont

Professor Emeritus of Computer Science, Mathematics, and the James Franck Institute
Ian Foster

Ian Foster

Arthur Holly Compton Distinguished Service Professor of Computer Science
Robert Grossman

Robert Grossman

Frederick H. Rawson Distinguished Service Professor in Medicine, Computer Science
Rana Hanocka

Rana Hanocka

Assistant Professor of Computer Science

Kate Keahey

Senior Scientist, CASE Affiliate
Gordon Kindlmann

Gordon Kindlmann

Associate Professor of Computer Science
Rick Stevens

Rick Stevens

Professor of Computer Science
headshot

Rebecca Willett

Worah Family Professor in the Wallman Society of Fellows, Computer Science, Statistics, and the College

News & Events

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UChicago CS News

Innovation at the Forefront: UChicago CS Researchers Make Significant Contributions to CHI 2025

Apr 23, 2025
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UChicago CS News

The University of Chicago Hosts the First Great Lakes Graphics Workshop

Apr 23, 2025
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In the News

Quantum Materials, Built By AI Robot

Apr 22, 2025
UChicago CS News

New Research Explores Augmented Breathing Through Thermal Feedback

Apr 21, 2025
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UChicago CS News

University of Chicago’s Fred Chong Awarded $2 Million for Innovative Quantum Computing Cancer Research Project

Apr 04, 2025
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UChicago CS News

Helping Elementary School Children Learn About Digital Privacy and Security With Micro-Lessons

Mar 25, 2025
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UChicago CS News

New Study Reveals Gaps in Common Types of Cybersecurity Training

Mar 24, 2025
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UChicago CS News

Jasmine Lu on Sustainable Computing: Rethinking E-Waste and Innovation

Mar 18, 2025
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UChicago CS News

Pedro Lopes Honored with 2025 IEEE VGTC Virtual Reality Significant New Researcher Award

Mar 13, 2025
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UChicago CS News

University of Chicago Researchers Revolutionize Network Traffic Generation with AI Breakthrough

Mar 12, 2025
UChicago CS News

Federal budget cuts threaten to decimate America’s AI superiority—and other countries are watching

Feb 25, 2025
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UChicago CS News

The Hidden Cost of Netflix’s Autoplay: A Study on Viewing Patterns and User Control

Feb 25, 2025
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